HAEMOPHILIA (hemophilia)

What is haemophilia?
Haemophilia is a group of genetic disorders that impair the body's capability to control blood clotting when a blood vessel breaks. Haemophilia is more common in males than females. In fact, females almost never have haemophilia. This is because females have 2 X chromosomes, so the chance of a female having two defective copies of the gene is very low. However, they can still carry it in their genes. There are also different types of haemophilia. Here they are:

There are 3 types of haemophilia:

Haemophilia A
Haemophilia A is the most common type of haemophilia, though it appears in many different forms of mutations. It occurs once in every 5000 to 10,000 male births. It represents 80% of all haemophilia cases. Haemophilia A is usually associated with serious bleeding. It usually bleeds in these areas:
  • joints
  • muscles
  • digestive tract
  • brain
All of these places are also the places with the most serious bleeding.

Haemophilia B (Christmas Disease)
Haemophilia B is caused by the mutation of the Factor IX gene. The Factor IX gene deficiency causes an increase for haemorrhage (bleeding). It is less common than Haemophilia A, for it only makes up 20% of the haemophilia cases.

Hameophilia C
Haemophilia C is a mild form of haemophilia. It is the only form of haemophilia which affects both genders. It usually appears in people of Jewish descent. It is very different from haemophilia A and B, because it doesn't cause bleeding of joints. Though it has many forms of mutations, it is by far the most rare form of haemophilia.

Preventing Haemophilia
Currently, about 17,000 people in the USA have haemophilia. How can we prevent this? Most of the time, haemophilia cannot be avoided, since it is hereditary, but you can always avoid activities which may cause bleeding. You can also get a genetic test and seek help from a professional, but avoid medicines that promote bleeding, like asprin.




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